Peyronie’s disease (Penis deformation): causes, symptoms and treatment

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Peyronie’s disease (Penis deformation): causes, symptoms and treatment
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Peyronie’s disease is when the penis becomes deformed forming a pronounced curved shape when erected.  A new treatment has been brought to market so suffers of this disease can avoid surgery and improve their sex life.  

What is Peyronie’s disease?

Peyronie’s disease is when the penis forms a curved shape when erected.  This is caused by a loss of cavernous body elasticity meaning the spongy and stretchy tissues found in the penis.  This phenomenon is called a fibrosis.  In the majority of cases the penis curves upwards and the angle a can range from 10 to 90 degrees

This deformation can make penetration and sexual relations more difficult and can even be painful.  Peyronie’s  disease seems to mostly affect men over the age of 50 years old.

What are the symptoms of Peyronie’s disease?

In the majority of cases the first inflammatory symptom of this disease is a painful and spontaneous erection.  Others say that the penis becomes increasingly curved over several weeks or months.

The disease evolves over 12 to 18 months. After a year, the pain dims for most sufferers (90%) however many still suffer from a curved penis when erected. (40%)

What is this new treatment?

A  new treatment has been offered in Britain to treat Peyronie’s disease called XIAPEX or XIAFLEX.  It is an  enzyme injection of collagenase clostridium histolyticum.  This treatment can be injected at any stage of the illness.

Two injections are required for this treatment at two or three day intervals. However depending on the severity of the fibrosis the sufferer can receive up to 8 injections with two to three months between each.  XIAFLEX induces moderate and transient side effects.

According the results of clinical trials, 60 to 70% of suffers saw an improvement in their symptoms with a lesser curve of about 15 to 20 degrees which allows them to avoid having surgery.


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